- Cytologic Findings of Clear Cell Adenocarcinoma of the Urethra: A Case Report
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Jee-Young Han, Kyu-Ho Kim, Lucia Kim, Suk-Jin Choi, In-Suh Park, Joon-Mee Kim, Young-Chae Chu, Sang-Min Yoon
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Korean J Pathol. 2012;46(2):210-214. Published online April 25, 2012
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DOI: https://doi.org/10.4132/KoreanJPathol.2012.46.2.210
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Abstract
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Clear cell adenocarcinoma of the urethra is a rare disease entity with an uncertain histogenesis. Here, we present a case of primary clear cell adenocarcinoma of the female urethra with its cytological findings. A 54-year-old woman presented with a painless gross hematuria lasting 3 months. On vaginal sonography, there was a sausage-like, elongated mass in the urethra, measuring 3.8×4.3 cm. The voided urine cytology revealed small clusters of rounded or papillary cells. The necrotic debris and inflammatory cells were present within some clusters of tumor cells. These tumor cells were enlarged and had abundant clear or granular cytoplasm with cytoplasmic vacuoles. The nucleus was granular and contained vesicular chromatin with prominent nucleoli. The hobnail cells and hyaline globules were also present as in a histologic section. The histologic findings were compatible with clear cell adenocarcinoma. The tumor showed distinctive cytological features. Cytologically, however, it is necessary to make a differential diagnosis from other adenocarcinoma or high-grade urothelial carcinoma.
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Citations
Citations to this article as recorded by
- Cytological and histological findings of upper tract mucinous urothelial carcinoma with clear cell component: A case report and review of literature
Go Kobayashi, Naohiro Uraoka, Kazuhiro Sentani, Jun Shibata, Ryosuke Nobuhiro, Yoichi Saito, Daiki Taniyama, Masanori Hanamoto, Hiroyuki Nose, Naohide Oue Diagnostic Cytopathology.2022;[Epub] CrossRef - Presentación de reporte de caso: adenocarcinoma de célula clara de uretra
Nataly González, Yuly Ramirez, Jose Szelezsán, Daniel Rojas Revista Urología Colombiana / Colombian Urology Journal.2018; 27(02): 191. CrossRef - Clear Cell Adenocarcinoma of the Urethra: Review of the Literature
Anthony Kodzo-Grey Venyo International Journal of Surgical Oncology.2015; 2015: 1. CrossRef
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